KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer

Failure to achieve complete elimination of triple negative breast cancer (TNBC) stem cells after adjuvant therapy is associated with poor outcomes. Aldehyde dehydrogenase 1 (ALDH1) is a marker of breast cancer stem cells (BCSCs), and its enzymatic activity regulates tumor stemness. Identifying upstr...

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Detalles Bibliográficos
Autores principales: Bu, Jiawen, Zhang, Yixiao, Wu, Sijin, Li, Haonan, Sun, Lisha, Liu, Yang, Zhu, Xudong, Qiao, Xinbo, Ma, Qingtian, Liu, Chao, Niu, Nan, Xue, Jinqi, Chen, Guanglei, Yang, Yongliang, Liu, Caigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163259/
https://www.ncbi.nlm.nih.gov/pubmed/37147285
http://dx.doi.org/10.1038/s41467-023-38097-1

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