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Biology and therapeutic targeting of molecular mechanisms in MPNs

Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by activated Janus kinase (JAK)–signal transducer and activator of transcription signaling. As a result, JAK inhibitors have been the standard therapy for treatment of patients with myelofibrosis (MF). Alt...

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Detalles Bibliográficos
Autores principales: How, Joan, Garcia, Jacqueline S., Mullally, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163317/
https://www.ncbi.nlm.nih.gov/pubmed/36534936
http://dx.doi.org/10.1182/blood.2022017416

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