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Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis
Antimicrobial peptides (AMPs) are innate immune effectors first studied for their role in host defence. Recent studies have implicated these peptides in the clearance of aberrant cells and in neurodegenerative syndromes. In Drosophila, many AMPs are produced downstream of Toll and Imd NF-κB pathways...
Autores principales: | Hanson, Mark A., Lemaitre, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163324/ https://www.ncbi.nlm.nih.gov/pubmed/36847474 http://dx.doi.org/10.1242/dmm.049965 |
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