Development of the aganglionic colon following surgical rescue in a cell therapy model of Hirschsprung disease in rat

Patients with Hirschsprung disease lack enteric ganglia in the distal colon and propulsion of colorectal content is substantially impaired. Proposed stem cell therapies to replace neurons require surgical bypass of the aganglionic bowel during re-colonization, but there is inadequate knowledge of th...

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Detalles Bibliográficos
Autores principales: Furness, John B., Lei, Enie, Hunne, Billie, Adams, Cameron D., Burns, Alan J., Wykosky, Jill, Fazio Coles, Therese E., Fothergill, Linda J., Molero, Juan C., Pustovit, Ruslan V., Stamp, Lincon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163357/
https://www.ncbi.nlm.nih.gov/pubmed/37021517
http://dx.doi.org/10.1242/dmm.050055

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