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Addressing resistance to PD-1/PD-(L)1 pathway inhibition: considerations for combinatorial clinical trial designs
With multiple PD-(L)1 inhibitors approved across dozens of indications by the US Food and Drug Administration, the number of patients exposed to these agents in adjuvant, first-line metastatic, second-line metastatic, and refractory treatment settings is increasing rapidly. Although some patients wi...
Autores principales: | Zhang, Tian, Forde, Patrick M, Sullivan, Ryan J, Sharon, Elad, Barksdale, Elizabeth, Selig, Wendy, Ebbinghaus, Scot, Fusaro, Gina, Gunenc, Damla, Battle, Dena, Burns, Robyn, Hurlbert, Marc S, Stewart, Mark, Atkins, Michael B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163527/ https://www.ncbi.nlm.nih.gov/pubmed/37137552 http://dx.doi.org/10.1136/jitc-2022-006555 |
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