CD73 and PD-L1 dual blockade amplifies antitumor efficacy of SBRT in murine PDAC models

BACKGROUND: Stereotactic body radiotherapy (SBRT) induces immunogenic cell death, leading to subsequent antitumor immune response that is in part counterbalanced by activation of immune evasive processes, for example, upregulation of programmed cell death-ligand 1 (PD-L1) and adenosine generating en...

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Detalles Bibliográficos
Autores principales: Ye, Jian, Gavras, Nicholas W, Keeley, David C, Hughson, Angela L, Hannon, Gary, Vrooman, Tara G, Lesch, Maggie L, Johnston, Carl J, Lord, Edith M, Belt, Brian A, Linehan, David C, Eyles, Jim, Gerber, Scott A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163599/
https://www.ncbi.nlm.nih.gov/pubmed/37142292
http://dx.doi.org/10.1136/jitc-2023-006842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163599/
https://www.ncbi.nlm.nih.gov/pubmed/37142292
http://dx.doi.org/10.1136/jitc-2023-006842

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