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17β-oestradiol inhibits ferroptosis in the hippocampus by upregulating DHODH and further improves memory decline after ovariectomy

Ovariectomy (OVX) conducted before the onset of natural menopause is considered to bringing forward and accelerate the process of ageing-associated neurodegeneration. However, the mechanisms underlying memory decline and other cognitive dysfunctions following OVX are unclear. Given that iron accumul...

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Detalles Bibliográficos
Autores principales: Tian, Ying, Xie, Yuan, Guo, Zaixin, Feng, Penghui, You, Yang, Yu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163677/
https://www.ncbi.nlm.nih.gov/pubmed/37116254
http://dx.doi.org/10.1016/j.redox.2023.102708