Cargando…
Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion
Pulmonary fibrosis (PF) is an interstitial lung disease with complex pathological mechanism, and there is currently a lack of therapeutics that can heal it completely. Using gene therapy with drugs provides promising therapeutic strategies for synergistically reversing PF. However, improving the int...
Autores principales: | Chang, Xin, Liu, Chang, Han, Yu-Mo, Li, Qiu-Ling, Guo, Bin, Jiang, Hu-Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163678/ https://www.ncbi.nlm.nih.gov/pubmed/37159604 http://dx.doi.org/10.1016/j.omtn.2023.04.006 |
Ejemplares similares
-
Higher pNRF2, SOCS3, IRF3, and RIG1 Tissue Protein Expression in NASH Patients versus NAFL Patients: pNRF2 Expression Is Concomitantly Associated with Elevated Fasting Glucose Levels
por: Schwertheim, Suzan, et al.
Publicado: (2023) -
Engineering of Stimulus-Responsive Pirfenidone Liposomes for Pulmonary Delivery During Treatment of Idiopathic Pulmonary Fibrosis
por: Han, Meishan, et al.
Publicado: (2022) -
Pirfenidone-loaded liposomes for lung targeting: preparation and in vitro/in vivo evaluation
por: Meng, Hui, et al.
Publicado: (2015) -
Preparation, characterization, and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes
por: Samadikhah, Hamid Reza, et al.
Publicado: (2011) -
Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium
por: Liu, Yuan, et al.
Publicado: (2017)