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Analytical quality-by-design approach for development and validation of HPLC method for the simultaneous estimation of omarigliptin, metformin, and ezetimibe: application to human plasma and dosage forms

A simple, selective, and sensitive RP-HPLC method was proposed for the simultaneous determination of two co-administered antidiabetic drugs (omarigliptin and metformin) with an anti-hyperlipidemic drug (ezetimibe) in a medicinally-recommended ratio of 2.5:50:1, respectively. The proposed procedure w...

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Detalles Bibliográficos
Autores principales: Magdy, Galal, Al-enna, Amira A., Belal, Fathalla, El-Domany, Ramadan A., Abdel-Megied, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163694/
https://www.ncbi.nlm.nih.gov/pubmed/37147652
http://dx.doi.org/10.1186/s13065-023-00955-w