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Analytical quality-by-design approach for development and validation of HPLC method for the simultaneous estimation of omarigliptin, metformin, and ezetimibe: application to human plasma and dosage forms
A simple, selective, and sensitive RP-HPLC method was proposed for the simultaneous determination of two co-administered antidiabetic drugs (omarigliptin and metformin) with an anti-hyperlipidemic drug (ezetimibe) in a medicinally-recommended ratio of 2.5:50:1, respectively. The proposed procedure w...
Autores principales: | Magdy, Galal, Al-enna, Amira A., Belal, Fathalla, El-Domany, Ramadan A., Abdel-Megied, Ahmed M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163694/ https://www.ncbi.nlm.nih.gov/pubmed/37147652 http://dx.doi.org/10.1186/s13065-023-00955-w |
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