Cardiac-targeted delivery of nuclear receptor RORα via ultrasound targeted microbubble destruction optimizes the benefits of regular dose of melatonin on sepsis-induced cardiomyopathy

BACKGROUND: Large-dose melatonin treatment in animal experiments was hardly translated into humans, which may explain the dilemma that the protective effects against myocardial injury in animal have been challenged by clinical trials. Ultrasound-targeted microbubble destruction (UTMD) has been consi...

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Detalles Bibliográficos
Autores principales: Wang, Shanjie, Chen, Kegong, Wang, Ye, Wang, Zeng, Li, Zhaoying, Guo, JunChen, Chen, Jianfeng, Liu, Wenhua, Guo, Xiaohui, Yan, Guangcan, Liang, Chenchen, Yu, Huai, Fang, Shaohong, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163781/
https://www.ncbi.nlm.nih.gov/pubmed/37147703
http://dx.doi.org/10.1186/s40824-023-00377-8

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