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Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer’s disease

BACKGROUND: Studies on DNA methylation (DNAm) in Alzheimer’s disease (AD) have recently highlighted several genomic loci showing association with disease onset and progression. METHODS: Here, we conducted an epigenome-wide association study (EWAS) using DNAm profiles in entorhinal cortex (EC) from 1...

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Detalles Bibliográficos
Autores principales: Sommerer, Yasmine, Dobricic, Valerija, Schilling, Marcel, Ohlei, Olena, Sabet, Sanaz Sedghpour, Wesse, Tanja, Fuß, Janina, Franzenburg, Sören, Franke, Andre, Parkkinen, Laura, Lill, Christina M., Bertram, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163801/
https://www.ncbi.nlm.nih.gov/pubmed/37149695
http://dx.doi.org/10.1186/s13195-023-01232-7