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Deciphering and advancing CAR T-cell therapy with single-cell sequencing technologies

Chimeric antigen receptor (CAR) T-cell therapy has made remarkable progress in cancer immunotherapy, but several challenges with unclear mechanisms hinder its wide clinical application. Single-cell sequencing technologies, with the powerful unbiased analysis of cellular heterogeneity and molecular p...

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Detalles Bibliográficos
Autores principales: Huang, Shengkang, Wang, Xinyu, Wang, Yu, Wang, Yajing, Fang, Chenglong, Wang, Yazhuo, Chen, Sifei, Chen, Runkai, Lei, Tao, Zhang, Yuchen, Xu, Xinjie, Li, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163813/
https://www.ncbi.nlm.nih.gov/pubmed/37149643
http://dx.doi.org/10.1186/s12943-023-01783-1