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Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019

PURPOSE: Since 2012 fentanyl-detected fatal overdoses have risen from 4% of all fatal overdoses in Connecticut to 82% in 2019. We aimed to investigate the geographic and temporal trends in fentanyl-detected deaths in Connecticut during 2009–2019. METHODS: Data on the dates and locations of accidenta...

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Autores principales: Lu, Haidong, Crawford, Forrest W., Gonsalves, Gregg S., Grau, Lauretta E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163838/
https://www.ncbi.nlm.nih.gov/pubmed/36669599
http://dx.doi.org/10.1016/j.annepidem.2023.01.009
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author Lu, Haidong
Crawford, Forrest W.
Gonsalves, Gregg S.
Grau, Lauretta E.
author_facet Lu, Haidong
Crawford, Forrest W.
Gonsalves, Gregg S.
Grau, Lauretta E.
author_sort Lu, Haidong
collection PubMed
description PURPOSE: Since 2012 fentanyl-detected fatal overdoses have risen from 4% of all fatal overdoses in Connecticut to 82% in 2019. We aimed to investigate the geographic and temporal trends in fentanyl-detected deaths in Connecticut during 2009–2019. METHODS: Data on the dates and locations of accidental/undetermined opioid-detected fatalities were obtained from Connecticut Office of the Chief Medical Examiner. Using a Bayesian space-time binomial model, we estimated spatiotemporal trends in the proportion of fentanyl-detected deaths. RESULTS: During 2009–2019, a total of 6,632 opioid deaths were identified. Among these, 3234 (49%) were fentanyl-detected. The modeled spatial patterns suggested that opioid deaths in northeastern Connecticut had higher probability of being fentanyl-detected, while New Haven and its neighboring towns and the southwestern region of Connecticut, primarily Greenwich, had a lower risk. Model estimates also suggested fentanyl-detected deaths gradually overtook the preceding non-fentanyl opioid-detected deaths across Connecticut. The estimated temporal trend showed the probability of fentanyl involvement increased substantially since 2014. CONCLUSIONS: Our findings suggest that geographic variation exists in the probability of fentanyl-detected deaths, and areas at heightened risk are identified. Further studies are warranted to explore potential factors contributing to the geographic heterogeneity and continuing dispersion of fentanyl-detected deaths in Connecticut.
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spelling pubmed-101638382023-05-06 Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019 Lu, Haidong Crawford, Forrest W. Gonsalves, Gregg S. Grau, Lauretta E. Ann Epidemiol Article PURPOSE: Since 2012 fentanyl-detected fatal overdoses have risen from 4% of all fatal overdoses in Connecticut to 82% in 2019. We aimed to investigate the geographic and temporal trends in fentanyl-detected deaths in Connecticut during 2009–2019. METHODS: Data on the dates and locations of accidental/undetermined opioid-detected fatalities were obtained from Connecticut Office of the Chief Medical Examiner. Using a Bayesian space-time binomial model, we estimated spatiotemporal trends in the proportion of fentanyl-detected deaths. RESULTS: During 2009–2019, a total of 6,632 opioid deaths were identified. Among these, 3234 (49%) were fentanyl-detected. The modeled spatial patterns suggested that opioid deaths in northeastern Connecticut had higher probability of being fentanyl-detected, while New Haven and its neighboring towns and the southwestern region of Connecticut, primarily Greenwich, had a lower risk. Model estimates also suggested fentanyl-detected deaths gradually overtook the preceding non-fentanyl opioid-detected deaths across Connecticut. The estimated temporal trend showed the probability of fentanyl involvement increased substantially since 2014. CONCLUSIONS: Our findings suggest that geographic variation exists in the probability of fentanyl-detected deaths, and areas at heightened risk are identified. Further studies are warranted to explore potential factors contributing to the geographic heterogeneity and continuing dispersion of fentanyl-detected deaths in Connecticut. 2023-03 2023-01-18 /pmc/articles/PMC10163838/ /pubmed/36669599 http://dx.doi.org/10.1016/j.annepidem.2023.01.009 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Article
Lu, Haidong
Crawford, Forrest W.
Gonsalves, Gregg S.
Grau, Lauretta E.
Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
title Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
title_full Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
title_fullStr Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
title_full_unstemmed Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
title_short Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
title_sort geographic and temporal trends in fentanyl-detected deaths in connecticut, 2009–2019
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163838/
https://www.ncbi.nlm.nih.gov/pubmed/36669599
http://dx.doi.org/10.1016/j.annepidem.2023.01.009
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