Biochemical characterization of actin assembly mechanisms with ALS-associated profilin variants

Eight separate mutations in the actin-binding protein profilin-1 have been identified as a rare cause of amyotrophic lateral sclerosis (ALS). Profilin is essential for many neuronal cell processes through its regulation of lipids, nuclear signals, and cytoskeletal dynamics, including actin filament...

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Detalles Bibliográficos
Autores principales: Liu, Xinbei, Pimm, Morgan L., Haarer, Brian, Brawner, Andrew T., Henty-Ridilla, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163920/
https://www.ncbi.nlm.nih.gov/pubmed/35248815
http://dx.doi.org/10.1016/j.ejcb.2022.151212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163920/
https://www.ncbi.nlm.nih.gov/pubmed/35248815
http://dx.doi.org/10.1016/j.ejcb.2022.151212

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