Silencing Notch4 promotes tumorigenesis and inhibits metastasis of triple-negative breast cancer via Nanog and Cdc42

Elucidation of individual Notch protein biology in specific cancer is crucial to develop safe, effective, and tumor-selective Notch-targeting therapeutic reagents for clinical use [1]. Here, we explored the Notch4 function in triple-negative breast cancer (TNBC). We found that silencing Notch4 enhan...

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Detalles Bibliográficos
Autores principales: Tian, Yuan, Zhang, Peipei, Mou, Yajun, Yang, Wenxiu, Zhang, Junhong, Li, Qing, Dou, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164131/
https://www.ncbi.nlm.nih.gov/pubmed/37149651
http://dx.doi.org/10.1038/s41420-023-01450-w

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