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Broad phosphorylation mediated by testis-specific serine/threonine kinases contributes to spermiogenesis and male fertility

Genetic studies elucidate a link between testis-specific serine/threonine kinases (TSSKs) and male infertility in mammals, but the underlying mechanisms are unclear. Here, we identify a TSSK homolog in Drosophila, CG14305 (termed dTSSK), whose mutation impairs the histone-to-protamine transition dur...

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Detalles Bibliográficos
Autores principales: Zhang, Xuedi, Peng, Ju, Wu, Menghua, Sun, Angyang, Wu, Xiangyu, Zheng, Jie, Shi, Wangfei, Gao, Guanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164148/
https://www.ncbi.nlm.nih.gov/pubmed/37149634
http://dx.doi.org/10.1038/s41467-023-38357-0