A Case of Acute Encephalopathy After the Initiation of FOLFOX Chemotherapy in a Patient With Colon Cancer

Acute encephalopathy is a change in the level of consciousness where the underlying etiology can be difficult to diagnose, and thus, difficult to treat, especially in the context of multi-organ diseases. We report a case of acute encephalopathy in a patient with end-stage renal disease (ESRD) on hem...

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Detalles Bibliográficos
Autores principales: Kim, Jin S, Lio, Ka U, Henderson, Hannah, Pourshahid, Seyedmohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164293/
https://www.ncbi.nlm.nih.gov/pubmed/37162780
http://dx.doi.org/10.7759/cureus.37237
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author Kim, Jin S
Lio, Ka U
Henderson, Hannah
Pourshahid, Seyedmohammad
author_facet Kim, Jin S
Lio, Ka U
Henderson, Hannah
Pourshahid, Seyedmohammad
author_sort Kim, Jin S
collection PubMed
description Acute encephalopathy is a change in the level of consciousness where the underlying etiology can be difficult to diagnose, and thus, difficult to treat, especially in the context of multi-organ diseases. We report a case of acute encephalopathy in a patient with end-stage renal disease (ESRD) on hemodialysis, chronic hypotension, and a recent diagnosis of colon cancer who presented shortly after initiation of FOLFOX, a chemotherapy regimen for treatment of colorectal cancer comprised of folinic acid (leucovorin), fluorouracil (5-FU), and oxaliplatin (eloxatin). We present a systematic approach to elucidate ambiguous causes of toxic-metabolic encephalopathy.
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spelling pubmed-101642932023-05-08 A Case of Acute Encephalopathy After the Initiation of FOLFOX Chemotherapy in a Patient With Colon Cancer Kim, Jin S Lio, Ka U Henderson, Hannah Pourshahid, Seyedmohammad Cureus Internal Medicine Acute encephalopathy is a change in the level of consciousness where the underlying etiology can be difficult to diagnose, and thus, difficult to treat, especially in the context of multi-organ diseases. We report a case of acute encephalopathy in a patient with end-stage renal disease (ESRD) on hemodialysis, chronic hypotension, and a recent diagnosis of colon cancer who presented shortly after initiation of FOLFOX, a chemotherapy regimen for treatment of colorectal cancer comprised of folinic acid (leucovorin), fluorouracil (5-FU), and oxaliplatin (eloxatin). We present a systematic approach to elucidate ambiguous causes of toxic-metabolic encephalopathy. Cureus 2023-04-07 /pmc/articles/PMC10164293/ /pubmed/37162780 http://dx.doi.org/10.7759/cureus.37237 Text en Copyright © 2023, Kim et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Kim, Jin S
Lio, Ka U
Henderson, Hannah
Pourshahid, Seyedmohammad
A Case of Acute Encephalopathy After the Initiation of FOLFOX Chemotherapy in a Patient With Colon Cancer
title A Case of Acute Encephalopathy After the Initiation of FOLFOX Chemotherapy in a Patient With Colon Cancer
title_full A Case of Acute Encephalopathy After the Initiation of FOLFOX Chemotherapy in a Patient With Colon Cancer
title_fullStr A Case of Acute Encephalopathy After the Initiation of FOLFOX Chemotherapy in a Patient With Colon Cancer
title_full_unstemmed A Case of Acute Encephalopathy After the Initiation of FOLFOX Chemotherapy in a Patient With Colon Cancer
title_short A Case of Acute Encephalopathy After the Initiation of FOLFOX Chemotherapy in a Patient With Colon Cancer
title_sort case of acute encephalopathy after the initiation of folfox chemotherapy in a patient with colon cancer
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164293/
https://www.ncbi.nlm.nih.gov/pubmed/37162780
http://dx.doi.org/10.7759/cureus.37237
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