Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X

BACKGROUND: Endothelial injury caused by Type 2 diabetes mellitus (T2DM) is considered as a mainstay in the pathophysiology of diabetic vascular complications (DVCs). However, the molecular mechanism of T2DM-induced endothelial injury remains largely unknown. Here, we found that endothelial WW domai...

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Detalles Bibliográficos
Autores principales: You, Shilong, Xu, Jiaqi, Yin, Zeyu, Wu, Boquan, Wang, Pengbo, Hao, Mingjun, Cheng, Cheng, Liu, Mengke, Zhao, Yuanhui, Jia, Pengyu, Jiang, Hongkun, Li, Da, Cao, Liu, Zhang, Xingang, Zhang, Ying, Sun, Yingxian, Zhang, Naijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164326/
https://www.ncbi.nlm.nih.gov/pubmed/37149668
http://dx.doi.org/10.1186/s12933-023-01818-3

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