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Widely spaced and divergent inverted repeats become a potent source of chromosomal rearrangements in long single-stranded DNA regions

DNA inverted repeats (IRs) are widespread across many eukaryotic genomes. Their ability to form stable hairpin/cruciform secondary structures is causative in triggering chromosome instability leading to several human diseases. Distance and sequence divergence between IRs are inversely correlated wit...

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Detalles Bibliográficos
Autores principales:	Ait Saada, Anissia, Guo, Wenying, Costa, Alex B, Yang, Jiaxin, Wang, Jianrong, Lobachev, Kirill S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164571/ https://www.ncbi.nlm.nih.gov/pubmed/36919609 http://dx.doi.org/10.1093/nar/gkad153

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