DNA supercoiling-induced shapes alter minicircle hydrodynamic properties

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DNA in cells is organized in negatively supercoiled loops. The resulting torsional and bending strain allows DNA to adopt a surprisingly wide variety of 3-D shapes. This interplay between negative supercoiling, looping, and shape influences how DNA is stored, replicated, transcribed, repaired, and l...

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Detalles Bibliográficos
Autores principales: Waszkiewicz, Radost, Ranasinghe, Maduni, Fogg, Jonathan M, Catanese, Daniel J, Ekiel-Jeżewska, Maria L, Lisicki, Maciej, Demeler, Borries, Zechiedrich, Lynn, Szymczak, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164573/
https://www.ncbi.nlm.nih.gov/pubmed/36971110
http://dx.doi.org/10.1093/nar/gkad183
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