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SPIDR is required for homologous recombination during mammalian meiosis
Meiotic recombinases RAD51 and DMC1 mediate strand exchange in the repair of DNA double-strand breaks (DSBs) by homologous recombination. This is a landmark event of meiosis that ensures genetic diversity in sexually reproducing organisms. However, the regulatory mechanism of DMC1/RAD51-ssDNA nucleo...
Autores principales: | Huang, Tao, Wu, Xinyue, Wang, Shiyu, Bao, Ziyou, Wan, Yanling, Wang, Ziqi, Li, Mengjing, Yu, Xiaochen, Lv, Yue, Liu, Zhaojian, Chen, Xiangfeng, Chan, Wai-Yee, Gao, Fei, Lu, Gang, Chen, Zi-Jiang, Liu, Hongbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164582/ https://www.ncbi.nlm.nih.gov/pubmed/36938872 http://dx.doi.org/10.1093/nar/gkad154 |
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