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A dual-purpose polymerase engineered for direct sequencing of pseudouridine and queuosine

More than 170 posttranscriptional RNA modifications are so far known on both coding and noncoding RNA species. Within this group, pseudouridine (Ψ) and queuosine (Q) represent conserved RNA modifications with fundamental functional roles in regulating translation. Current detection methods of these...

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Detalles Bibliográficos
Autores principales: Huber, Luisa B, Kaur, Navpreet, Henkel, Melanie, Marchand, Virginie, Motorin, Yuri, Ehrenhofer-Murray, Ann E, Marx, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164586/
https://www.ncbi.nlm.nih.gov/pubmed/36971106
http://dx.doi.org/10.1093/nar/gkad177

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