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A dual-purpose polymerase engineered for direct sequencing of pseudouridine and queuosine
More than 170 posttranscriptional RNA modifications are so far known on both coding and noncoding RNA species. Within this group, pseudouridine (Ψ) and queuosine (Q) represent conserved RNA modifications with fundamental functional roles in regulating translation. Current detection methods of these...
Autores principales: | Huber, Luisa B, Kaur, Navpreet, Henkel, Melanie, Marchand, Virginie, Motorin, Yuri, Ehrenhofer-Murray, Ann E, Marx, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164586/ https://www.ncbi.nlm.nih.gov/pubmed/36971106 http://dx.doi.org/10.1093/nar/gkad177 |
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