RNA binding proteins Smaug and Cup induce CCR4–NOT-dependent deadenylation of the nanos mRNA in a reconstituted system

Posttranscriptional regulation of the maternal nanos mRNA is essential for the development of the anterior – posterior axis of the Drosophila embryo. The nanos RNA is regulated by the protein Smaug, which binds to Smaug recognition elements (SREs) in the nanos 3’-UTR and nucleates the assembly of a...

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Detalles Bibliográficos
Autores principales: Pekovic, Filip, Rammelt, Christiane, Kubíková, Jana, Metz, Jutta, Jeske, Mandy, Wahle, Elmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164591/
https://www.ncbi.nlm.nih.gov/pubmed/36951092
http://dx.doi.org/10.1093/nar/gkad159

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