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Sickle cell disease is a risk factor for transplant-associated thrombotic microangiopathy in children

Transplant-associated thrombotic microangiopathy (TA-TMA) and sickle cell disease (SCD) share features of endothelial and complement activation. Thus, we hypothesized that SCD is a risk factor for TA-TMA and that prehematopoietic cellular transplantation (HCT) markers of endothelial dysfunction and...

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Detalles Bibliográficos
Autores principales: Schoettler, Michelle, Stenger, Elizabeth, Spencer, Kathleen, Lutterman, Deborah, Rumbika, Savanah, Jones, Jayre, Haight, Ann, Parikh, Suhag, Qayed, Muna, Watkins, Benjamin, Krishnamurti, Lakshmanan, Williams, Kirsten M., Chonat, Satheesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164784/
https://www.ncbi.nlm.nih.gov/pubmed/36075028
http://dx.doi.org/10.1182/bloodadvances.2022008058