Cargando…
Pediatric Brucellosis: A Challenging Diagnosis—Case Report
BACKGROUND: Brucellosis is the second most widely spread zoonotic disease. There is less literature on this disease in Pakistan, leading to delayed diagnosis, or the patient remains undiagnosed. This study aims to contribute to Pediatric brucellosis literature, epidemiological, clinical features, la...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164848/ https://www.ncbi.nlm.nih.gov/pubmed/37148217 http://dx.doi.org/10.1177/21501319231170497 |
_version_ | 1785038134950494208 |
---|---|
author | Shaikh, Areeba Sarfaraz, Munira Ehsan, Shaista |
author_facet | Shaikh, Areeba Sarfaraz, Munira Ehsan, Shaista |
author_sort | Shaikh, Areeba |
collection | PubMed |
description | BACKGROUND: Brucellosis is the second most widely spread zoonotic disease. There is less literature on this disease in Pakistan, leading to delayed diagnosis, or the patient remains undiagnosed. This study aims to contribute to Pediatric brucellosis literature, epidemiological, clinical features, laboratory findings, and treatment. CASE PRESENTATION: We present an 11-year-old child who was admitted to the hospital due to abdominal pain for one month and a fever for 15 days. On abdominal ultrasound, she had hepato-splenomegaly with minimal pleural effusion. A comprehensive diagnostic workup for infectious and immunologic disorders confirmed brucellosis with the antibody tests report. She received doxycycline, rifampin, and trimethoprim-sulfamethoxazole for three months. The treatment was continued with Syrup Doxycycline (50 mg/5 ml), and Syrup Rifampicin (2 g/100 ml) was prescribed for five weeks. Her symptoms were improved by the end of the treatment. CONCLUSION: Brucella is an intracellular pathogen affecting multi-systems of the human body; thus, the treatment is started with antimicrobials that have penetrative effects on a cell. The treatment can be adjusted based on the age group and the complication of the symptoms. |
format | Online Article Text |
id | pubmed-10164848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-101648482023-05-09 Pediatric Brucellosis: A Challenging Diagnosis—Case Report Shaikh, Areeba Sarfaraz, Munira Ehsan, Shaista J Prim Care Community Health Case Studies BACKGROUND: Brucellosis is the second most widely spread zoonotic disease. There is less literature on this disease in Pakistan, leading to delayed diagnosis, or the patient remains undiagnosed. This study aims to contribute to Pediatric brucellosis literature, epidemiological, clinical features, laboratory findings, and treatment. CASE PRESENTATION: We present an 11-year-old child who was admitted to the hospital due to abdominal pain for one month and a fever for 15 days. On abdominal ultrasound, she had hepato-splenomegaly with minimal pleural effusion. A comprehensive diagnostic workup for infectious and immunologic disorders confirmed brucellosis with the antibody tests report. She received doxycycline, rifampin, and trimethoprim-sulfamethoxazole for three months. The treatment was continued with Syrup Doxycycline (50 mg/5 ml), and Syrup Rifampicin (2 g/100 ml) was prescribed for five weeks. Her symptoms were improved by the end of the treatment. CONCLUSION: Brucella is an intracellular pathogen affecting multi-systems of the human body; thus, the treatment is started with antimicrobials that have penetrative effects on a cell. The treatment can be adjusted based on the age group and the complication of the symptoms. SAGE Publications 2023-05-06 /pmc/articles/PMC10164848/ /pubmed/37148217 http://dx.doi.org/10.1177/21501319231170497 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Studies Shaikh, Areeba Sarfaraz, Munira Ehsan, Shaista Pediatric Brucellosis: A Challenging Diagnosis—Case Report |
title | Pediatric Brucellosis: A Challenging Diagnosis—Case Report |
title_full | Pediatric Brucellosis: A Challenging Diagnosis—Case Report |
title_fullStr | Pediatric Brucellosis: A Challenging Diagnosis—Case Report |
title_full_unstemmed | Pediatric Brucellosis: A Challenging Diagnosis—Case Report |
title_short | Pediatric Brucellosis: A Challenging Diagnosis—Case Report |
title_sort | pediatric brucellosis: a challenging diagnosis—case report |
topic | Case Studies |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164848/ https://www.ncbi.nlm.nih.gov/pubmed/37148217 http://dx.doi.org/10.1177/21501319231170497 |
work_keys_str_mv | AT shaikhareeba pediatricbrucellosisachallengingdiagnosiscasereport AT sarfarazmunira pediatricbrucellosisachallengingdiagnosiscasereport AT ehsanshaista pediatricbrucellosisachallengingdiagnosiscasereport |