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Pediatric Brucellosis: A Challenging Diagnosis—Case Report

BACKGROUND: Brucellosis is the second most widely spread zoonotic disease. There is less literature on this disease in Pakistan, leading to delayed diagnosis, or the patient remains undiagnosed. This study aims to contribute to Pediatric brucellosis literature, epidemiological, clinical features, la...

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Autores principales: Shaikh, Areeba, Sarfaraz, Munira, Ehsan, Shaista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164848/
https://www.ncbi.nlm.nih.gov/pubmed/37148217
http://dx.doi.org/10.1177/21501319231170497
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author Shaikh, Areeba
Sarfaraz, Munira
Ehsan, Shaista
author_facet Shaikh, Areeba
Sarfaraz, Munira
Ehsan, Shaista
author_sort Shaikh, Areeba
collection PubMed
description BACKGROUND: Brucellosis is the second most widely spread zoonotic disease. There is less literature on this disease in Pakistan, leading to delayed diagnosis, or the patient remains undiagnosed. This study aims to contribute to Pediatric brucellosis literature, epidemiological, clinical features, laboratory findings, and treatment. CASE PRESENTATION: We present an 11-year-old child who was admitted to the hospital due to abdominal pain for one month and a fever for 15 days. On abdominal ultrasound, she had hepato-splenomegaly with minimal pleural effusion. A comprehensive diagnostic workup for infectious and immunologic disorders confirmed brucellosis with the antibody tests report. She received doxycycline, rifampin, and trimethoprim-sulfamethoxazole for three months. The treatment was continued with Syrup Doxycycline (50 mg/5 ml), and Syrup Rifampicin (2 g/100 ml) was prescribed for five weeks. Her symptoms were improved by the end of the treatment. CONCLUSION: Brucella is an intracellular pathogen affecting multi-systems of the human body; thus, the treatment is started with antimicrobials that have penetrative effects on a cell. The treatment can be adjusted based on the age group and the complication of the symptoms.
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spelling pubmed-101648482023-05-09 Pediatric Brucellosis: A Challenging Diagnosis—Case Report Shaikh, Areeba Sarfaraz, Munira Ehsan, Shaista J Prim Care Community Health Case Studies BACKGROUND: Brucellosis is the second most widely spread zoonotic disease. There is less literature on this disease in Pakistan, leading to delayed diagnosis, or the patient remains undiagnosed. This study aims to contribute to Pediatric brucellosis literature, epidemiological, clinical features, laboratory findings, and treatment. CASE PRESENTATION: We present an 11-year-old child who was admitted to the hospital due to abdominal pain for one month and a fever for 15 days. On abdominal ultrasound, she had hepato-splenomegaly with minimal pleural effusion. A comprehensive diagnostic workup for infectious and immunologic disorders confirmed brucellosis with the antibody tests report. She received doxycycline, rifampin, and trimethoprim-sulfamethoxazole for three months. The treatment was continued with Syrup Doxycycline (50 mg/5 ml), and Syrup Rifampicin (2 g/100 ml) was prescribed for five weeks. Her symptoms were improved by the end of the treatment. CONCLUSION: Brucella is an intracellular pathogen affecting multi-systems of the human body; thus, the treatment is started with antimicrobials that have penetrative effects on a cell. The treatment can be adjusted based on the age group and the complication of the symptoms. SAGE Publications 2023-05-06 /pmc/articles/PMC10164848/ /pubmed/37148217 http://dx.doi.org/10.1177/21501319231170497 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Studies
Shaikh, Areeba
Sarfaraz, Munira
Ehsan, Shaista
Pediatric Brucellosis: A Challenging Diagnosis—Case Report
title Pediatric Brucellosis: A Challenging Diagnosis—Case Report
title_full Pediatric Brucellosis: A Challenging Diagnosis—Case Report
title_fullStr Pediatric Brucellosis: A Challenging Diagnosis—Case Report
title_full_unstemmed Pediatric Brucellosis: A Challenging Diagnosis—Case Report
title_short Pediatric Brucellosis: A Challenging Diagnosis—Case Report
title_sort pediatric brucellosis: a challenging diagnosis—case report
topic Case Studies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164848/
https://www.ncbi.nlm.nih.gov/pubmed/37148217
http://dx.doi.org/10.1177/21501319231170497
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