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Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis

Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved...

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Detalles Bibliográficos
Autores principales: Peng, Peng, Liu, Xiuyuan, Yang, Lin, Gu, Zhenguang, Cai, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164873/
https://www.ncbi.nlm.nih.gov/pubmed/37168526
http://dx.doi.org/10.1155/2023/9923428
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author Peng, Peng
Liu, Xiuyuan
Yang, Lin
Gu, Zhenguang
Cai, Lin
author_facet Peng, Peng
Liu, Xiuyuan
Yang, Lin
Gu, Zhenguang
Cai, Lin
author_sort Peng, Peng
collection PubMed
description Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved the information of 780 GCOM cases from the Surveillance, Epidemiology, and End Results (SEERs) database and analyzed their clinicopathological characteristics as well as their survival. According to our data, most GCOM patients showed poor pathological differentiation, advanced T and N stages. The prognostic factors include patients' age, tumor size, surgical resection, and chemotherapy treatment. Of note, the marriage status was also identified as an independent prognostic factor. Besides the identification of prognostic factors, we established nomograms to help predict the overall survival and cancer-specific survival of GCOM, respectively.
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spelling pubmed-101648732023-05-09 Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis Peng, Peng Liu, Xiuyuan Yang, Lin Gu, Zhenguang Cai, Lin Genet Res (Camb) Research Article Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved the information of 780 GCOM cases from the Surveillance, Epidemiology, and End Results (SEERs) database and analyzed their clinicopathological characteristics as well as their survival. According to our data, most GCOM patients showed poor pathological differentiation, advanced T and N stages. The prognostic factors include patients' age, tumor size, surgical resection, and chemotherapy treatment. Of note, the marriage status was also identified as an independent prognostic factor. Besides the identification of prognostic factors, we established nomograms to help predict the overall survival and cancer-specific survival of GCOM, respectively. Hindawi 2023-04-30 /pmc/articles/PMC10164873/ /pubmed/37168526 http://dx.doi.org/10.1155/2023/9923428 Text en Copyright © 2023 Peng Peng et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Peng, Peng
Liu, Xiuyuan
Yang, Lin
Gu, Zhenguang
Cai, Lin
Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_full Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_fullStr Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_full_unstemmed Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_short Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
title_sort systematically prognostic analyses of gastric cancer patients with ovarian metastasis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164873/
https://www.ncbi.nlm.nih.gov/pubmed/37168526
http://dx.doi.org/10.1155/2023/9923428
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