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Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis
Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164873/ https://www.ncbi.nlm.nih.gov/pubmed/37168526 http://dx.doi.org/10.1155/2023/9923428 |
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author | Peng, Peng Liu, Xiuyuan Yang, Lin Gu, Zhenguang Cai, Lin |
author_facet | Peng, Peng Liu, Xiuyuan Yang, Lin Gu, Zhenguang Cai, Lin |
author_sort | Peng, Peng |
collection | PubMed |
description | Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved the information of 780 GCOM cases from the Surveillance, Epidemiology, and End Results (SEERs) database and analyzed their clinicopathological characteristics as well as their survival. According to our data, most GCOM patients showed poor pathological differentiation, advanced T and N stages. The prognostic factors include patients' age, tumor size, surgical resection, and chemotherapy treatment. Of note, the marriage status was also identified as an independent prognostic factor. Besides the identification of prognostic factors, we established nomograms to help predict the overall survival and cancer-specific survival of GCOM, respectively. |
format | Online Article Text |
id | pubmed-10164873 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-101648732023-05-09 Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis Peng, Peng Liu, Xiuyuan Yang, Lin Gu, Zhenguang Cai, Lin Genet Res (Camb) Research Article Ovarian metastasis of gastric cancer indicates that the disease has reached the late stage and the opportunity for radical surgery is restricted. However, the clinical characteristics and prognosis of patients with gastric cancer ovarian metastasis (GCOM) remain to be illustrated. Here, we retrieved the information of 780 GCOM cases from the Surveillance, Epidemiology, and End Results (SEERs) database and analyzed their clinicopathological characteristics as well as their survival. According to our data, most GCOM patients showed poor pathological differentiation, advanced T and N stages. The prognostic factors include patients' age, tumor size, surgical resection, and chemotherapy treatment. Of note, the marriage status was also identified as an independent prognostic factor. Besides the identification of prognostic factors, we established nomograms to help predict the overall survival and cancer-specific survival of GCOM, respectively. Hindawi 2023-04-30 /pmc/articles/PMC10164873/ /pubmed/37168526 http://dx.doi.org/10.1155/2023/9923428 Text en Copyright © 2023 Peng Peng et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Peng, Peng Liu, Xiuyuan Yang, Lin Gu, Zhenguang Cai, Lin Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis |
title | Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis |
title_full | Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis |
title_fullStr | Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis |
title_full_unstemmed | Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis |
title_short | Systematically Prognostic Analyses of Gastric Cancer Patients with Ovarian Metastasis |
title_sort | systematically prognostic analyses of gastric cancer patients with ovarian metastasis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164873/ https://www.ncbi.nlm.nih.gov/pubmed/37168526 http://dx.doi.org/10.1155/2023/9923428 |
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