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Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism

Adipose tissue plays a crucial role in maintaining metabolic homeostasis by storing lipids and glucose from circulation as intracellular fat. As peripheral tissues like adipose tissue become insulin resistant, decompensation of blood glucose levels occurs causing type 2 diabetes (T2D). Currently, mo...

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Detalles Bibliográficos
Autores principales:	Trieger, Greg W., Pessentheiner, Ariane R., Purcell, Sean C., Green, Courtney R., DeForest, Natalie, Willert, Karl, Majithia, Amit R., Metallo, Christian M., Godula, Kamil, Gordts, Philip L.S.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article Collection: Glycobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164900/ https://www.ncbi.nlm.nih.gov/pubmed/36931394 http://dx.doi.org/10.1016/j.jbc.2023.104611

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