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Identification of nonhistone substrates of the lysine methyltransferase PRDM9

Lysine methylation is a dynamic, posttranslational mark that regulates the function of histone and nonhistone proteins. Many of the enzymes that mediate lysine methylation, known as lysine methyltransferases (KMTs), were originally identified to modify histone proteins but have also been discovered...

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Detalles Bibliográficos
Autores principales: Hanquier, Jocelyne N., Sanders, Kenidi, Berryhill, Christine A., Sahoo, Firoj K., Hudmon, Andy, Vilseck, Jonah Z., Cornett, Evan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164904/
https://www.ncbi.nlm.nih.gov/pubmed/36972790
http://dx.doi.org/10.1016/j.jbc.2023.104651