The intramembrane COOH-terminal domain of PRRT2 regulates voltage-dependent Na(+) channels

Proline-rich transmembrane protein 2 (PRRT2) is the single causative gene for pleiotropic paroxysmal syndromes, including epilepsy, kinesigenic dyskinesia, episodic ataxia, and migraine. PRRT2 is a neuron-specific type-2 membrane protein with a COOH-terminal intramembrane domain and a long proline-r...

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Detalles Bibliográficos
Autores principales: Franchi, Francesca, Marte, Antonella, Corradi, Beatrice, Sterlini, Bruno, Alberini, Giulio, Romei, Alessandra, De Fusco, Antonio, Vogel, Alexander, Maragliano, Luca, Baldelli, Pietro, Corradi, Anna, Valente, Pierluigi, Benfenati, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164911/
https://www.ncbi.nlm.nih.gov/pubmed/36958475
http://dx.doi.org/10.1016/j.jbc.2023.104632

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