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Interaction of LARP4 to filamin A mechanosensing domain regulates cell migrations
Filamin A (FLNA) is an actin cross-linking protein that mediates mechanotransduction. Force-dependent conformational changes of FLNA molecule expose cryptic binding site of FLNA, allowing interaction with partners such as integrin, smoothelin, and fimbacin. Here, we identified La-related protein 4 (...
Autores principales: | Mao, Zhenfeng, Nakamura, Fumihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164935/ https://www.ncbi.nlm.nih.gov/pubmed/37169020 http://dx.doi.org/10.3389/fcell.2023.1152109 |
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