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Radiation upregulates macrophage TREM-1 expression to exacerbate injury in mice

INTRODUCTION: Exposure to high-dose ionizing radiation causes tissue injury, infections and even death due to immune dysfunction. The triggering receptor expressed on myeloid cells-1 (TREM-1) has been demonstrated to critically amplify and dysregulate immune responses. However, the role of TREM-1 in...

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Detalles Bibliográficos
Autores principales: Yamaga, Satoshi, Murao, Atsushi, Ma, Gaifeng, Brenner, Max, Aziz, Monowar, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164953/
https://www.ncbi.nlm.nih.gov/pubmed/37168858
http://dx.doi.org/10.3389/fimmu.2023.1151250