ERBB family fusions are recurrent and actionable oncogenic targets across cancer types

PURPOSE: Gene fusions involving receptor tyrosine kinases (RTKs) define an important class of genomic alterations with many successful targeted therapies now approved for ALK, ROS1, RET and NTRK gene fusions. Fusions involving the ERBB family of RTKs have been sporadically reported, but their freque...

Descripción completa

Detalles Bibliográficos
Autores principales: Schubert, Laura, Elliott, Andrew, Le, Anh T., Estrada-Bernal, Adriana, Doebele, Robert C., Lou, Emil, Borghaei, Hossein, Demeure, Michael J., Kurzrock, Razelle, Reuss, Joshua E., Ou, Sai-Hong Ignatius, Braxton, David R., Thomas, Christian A., Darabi, Sourat, Korn, Wolfgang Michael, El-Deiry, Wafik S., Liu, Stephen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164992/
https://www.ncbi.nlm.nih.gov/pubmed/37168365
http://dx.doi.org/10.3389/fonc.2023.1115405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164992/
https://www.ncbi.nlm.nih.gov/pubmed/37168365
http://dx.doi.org/10.3389/fonc.2023.1115405

Ejemplares similares