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ERBB family fusions are recurrent and actionable oncogenic targets across cancer types
PURPOSE: Gene fusions involving receptor tyrosine kinases (RTKs) define an important class of genomic alterations with many successful targeted therapies now approved for ALK, ROS1, RET and NTRK gene fusions. Fusions involving the ERBB family of RTKs have been sporadically reported, but their freque...
Autores principales: | Schubert, Laura, Elliott, Andrew, Le, Anh T., Estrada-Bernal, Adriana, Doebele, Robert C., Lou, Emil, Borghaei, Hossein, Demeure, Michael J., Kurzrock, Razelle, Reuss, Joshua E., Ou, Sai-Hong Ignatius, Braxton, David R., Thomas, Christian A., Darabi, Sourat, Korn, Wolfgang Michael, El-Deiry, Wafik S., Liu, Stephen V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164992/ https://www.ncbi.nlm.nih.gov/pubmed/37168365 http://dx.doi.org/10.3389/fonc.2023.1115405 |
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