Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory

The postsynaptic inhibition through GABA(A) receptors (GABA(A)R) relies on two mechanisms, a shunting effect due to an increase in the postsynaptic membrane conductance and, in mature neurons, a hyperpolarization effect due to an entry of chloride into postsynaptic neurons. The second effect require...

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Detalles Bibliográficos
Autores principales: Kreis, Anna, Issa, Farah, Yerna, Xavier, Jabbour, Caren, Schakman, Olivier, de Clippele, Marie, Tajeddine, Nicolas, Pierrot, Nathalie, Octave, Jean-Noël, Gualdani, Roberta, Gailly, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164999/
https://www.ncbi.nlm.nih.gov/pubmed/37168681
http://dx.doi.org/10.3389/fnmol.2023.1081657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164999/
https://www.ncbi.nlm.nih.gov/pubmed/37168681
http://dx.doi.org/10.3389/fnmol.2023.1081657

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