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Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory
The postsynaptic inhibition through GABA(A) receptors (GABA(A)R) relies on two mechanisms, a shunting effect due to an increase in the postsynaptic membrane conductance and, in mature neurons, a hyperpolarization effect due to an entry of chloride into postsynaptic neurons. The second effect require...
Autores principales: | Kreis, Anna, Issa, Farah, Yerna, Xavier, Jabbour, Caren, Schakman, Olivier, de Clippele, Marie, Tajeddine, Nicolas, Pierrot, Nathalie, Octave, Jean-Noël, Gualdani, Roberta, Gailly, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10164999/ https://www.ncbi.nlm.nih.gov/pubmed/37168681 http://dx.doi.org/10.3389/fnmol.2023.1081657 |
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