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Demethyleneberberine alleviated the inflammatory response by targeting MD-2 to inhibit the TLR4 signaling

INTRODUCTION: The colitis induced by trinitrobenzenesulfonic acid (TNBS) is a chronic and systemic inflammatory disease that leads to intestinal barrier dysfunction and autoimmunedisorders. However, the existing treatments of colitis are associated with poor outcomes, and the current strategies rema...

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Detalles Bibliográficos
Autores principales: Zhao, Yaxing, Liu, Peng, Luan, Haofan, Jiang, Hua, Xu, Yingmei, Zhang, Yuanqiang, Zhang, Yubin, Li, Ruiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165096/
https://www.ncbi.nlm.nih.gov/pubmed/37168866
http://dx.doi.org/10.3389/fimmu.2023.1130404