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Variant biomarker discovery using mass spectrometry-based proteogenomics

Genomic diversity plays critical roles in risk of disease pathogenesis and diagnosis. While genomic variants—including single nucleotide variants, frameshift variants, and mis-splicing isoforms—are commonly detected at the DNA or RNA level, their translated variant protein or polypeptide products ar...

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Detalles Bibliográficos
Autores principales:	Reilly, Luke, Seddighi, Sahba, Singleton, Andrew B., Cookson, Mark R., Ward, Michael E., Qi, Yue A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Aging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165118/ https://www.ncbi.nlm.nih.gov/pubmed/37168844 http://dx.doi.org/10.3389/fragi.2023.1191993

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