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A synthetic peptide from Sipunculus nudus promotes bone formation via Estrogen/MAPK signal pathway based on network pharmacology

The tripeptide Leu-Pro-Lys (LPK), derived from the Sipunculus nudus protein, was synthesized and studied to investigate its potential protective effect on bone formation. The effect and mechanism of LPK were analyzed through network pharmacology, bioinformatics, and experimental pharmacology. The st...

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Detalles Bibliográficos
Autores principales:	Wang, Peiran, Feng, Zhenhui, Chen, Siyu, Liang, Yingye, Hou, Haiyan, Ouyang, Qianqian, Yu, Hui, Ye, Hua, Cai, Lei, Qi, Yi, Wu, Kefeng, Luo, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165119/ https://www.ncbi.nlm.nih.gov/pubmed/37168991 http://dx.doi.org/10.3389/fphar.2023.1173110

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