Itch receptor MRGPRX4 interacts with the receptor activity–modifying proteins

Cholestatic itch is a severe and debilitating symptom in liver diseases with limited treatment options. The class A G protein-coupled receptor (GPCR) Mas-related GPCR subtype X4 (MRGPRX4) has been identified as a receptor for bile acids, which are potential cholestatic pruritogens. An increasing num...

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Detalles Bibliográficos
Autores principales: Kotliar, Ilana B., Ceraudo, Emilie, Kemelmakher-Liben, Kevin, Oren, Deena A., Lorenzen, Emily, Dodig-Crnković, Tea, Horioka-Duplix, Mizuho, Huber, Thomas, Schwenk, Jochen M., Sakmar, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165273/
https://www.ncbi.nlm.nih.gov/pubmed/37003505
http://dx.doi.org/10.1016/j.jbc.2023.104664

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