Cargando…
KRAS, MYC, and ARF6: inseparable relationships cooperatively promote cancer malignancy and immune evasion
Mutations in the KRAS gene and overexpression of protein products of the MYC and ARF6 genes occur frequently in cancer. Here, the inseparable relationships and cooperation of the protein products of these three genes in cancer malignancy and immune evasion are discussed. mRNAs encoded by these genes...
Autor principal: | Sabe, Hisataka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165578/ https://www.ncbi.nlm.nih.gov/pubmed/37158894 http://dx.doi.org/10.1186/s12964-023-01130-3 |
Ejemplares similares
-
ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer
por: Hashimoto, Shigeru, et al.
Publicado: (2019) -
Inhibition of mutant KRAS-driven overexpression of ARF6 and MYC by an eIF4A inhibitor drug improves the effects of anti-PD-1 immunotherapy for pancreatic cancer
por: Hashimoto, Ari, et al.
Publicado: (2021) -
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer
por: Hashimoto, Shigeru, et al.
Publicado: (2016) -
MYC, Cell Competition, and Cell Death in Cancer: The Inseparable Triad
por: Di Giacomo, Simone, et al.
Publicado: (2017) -
Los inseparables /
por: Ravazzi, Gianni
Publicado: (2006)