Optimizing (O) rifapentine-based (RI) regimen and shortening (EN) the treatment of drug-susceptible tuberculosis (T) (ORIENT) using an adaptive seamless design: study protocol of a multicenter randomized controlled trial

BACKGROUND: Standard treatment for drug-susceptible tuberculosis (DS-TB) includes a multidrug regimen requiring at least 6 months of treatment, and this lengthy treatment easily leads to poor adherence. There is an urgent need to simplify and shorten treatment regimens to reduce interruption and adv...

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Detalles Bibliográficos
Autores principales: Feng, Zhen, Miao, Yan, Peng, Ying, Sun, Feng, Zhang, Yilin, Li, Rong, Ge, Shijia, Chen, Xinchang, Song, Lingyun, Li, Yang, Wang, Xiaomeng, Zhang, Wenhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165810/
https://www.ncbi.nlm.nih.gov/pubmed/37158831
http://dx.doi.org/10.1186/s12879-023-08264-2

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