Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period

We report an important case of periventricular white matter damage in a 1-month-old infant, demonstrated on high quality structural (T2) and diffusion weighted magnetic resonance imaging. The infant was born at term following an uneventful pregnancy and discharged home shortly after, but was brought...

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Autores principales: Cromb, Daniel, Finck, Tom, Quirke, Megan, Cawley, Paul, Moran, Amy, Banjoko, Olutoyin, Rutherford, Mary A, Arichi, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Illustrated
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165867/
https://www.ncbi.nlm.nih.gov/pubmed/37193002
http://dx.doi.org/10.1016/j.idcr.2023.e01796
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author Cromb, Daniel
Finck, Tom
Quirke, Megan
Cawley, Paul
Moran, Amy
Banjoko, Olutoyin
Rutherford, Mary A
Arichi, Tomoki
author_facet Cromb, Daniel
Finck, Tom
Quirke, Megan
Cawley, Paul
Moran, Amy
Banjoko, Olutoyin
Rutherford, Mary A
Arichi, Tomoki
author_sort Cromb, Daniel
collection PubMed
description We report an important case of periventricular white matter damage in a 1-month-old infant, demonstrated on high quality structural (T2) and diffusion weighted magnetic resonance imaging. The infant was born at term following an uneventful pregnancy and discharged home shortly after, but was brought to the paediatric emergency department five days after birth with seizures and respiratory distress, testing positive for COVID-19 infection on PCR. These images highlight the need to consider brain MRI in all infants with symptomatic SARS-Cov-2 infection, and show how this infection can lead to extensive white matter damage in the context of multisystem inflammation
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spelling pubmed-101658672023-05-09 Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period Cromb, Daniel Finck, Tom Quirke, Megan Cawley, Paul Moran, Amy Banjoko, Olutoyin Rutherford, Mary A Arichi, Tomoki IDCases Case Illustrated We report an important case of periventricular white matter damage in a 1-month-old infant, demonstrated on high quality structural (T2) and diffusion weighted magnetic resonance imaging. The infant was born at term following an uneventful pregnancy and discharged home shortly after, but was brought to the paediatric emergency department five days after birth with seizures and respiratory distress, testing positive for COVID-19 infection on PCR. These images highlight the need to consider brain MRI in all infants with symptomatic SARS-Cov-2 infection, and show how this infection can lead to extensive white matter damage in the context of multisystem inflammation Elsevier 2023-05-08 /pmc/articles/PMC10165867/ /pubmed/37193002 http://dx.doi.org/10.1016/j.idcr.2023.e01796 Text en © 2023 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Illustrated
Cromb, Daniel
Finck, Tom
Quirke, Megan
Cawley, Paul
Moran, Amy
Banjoko, Olutoyin
Rutherford, Mary A
Arichi, Tomoki
Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period
title Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period
title_full Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period
title_fullStr Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period
title_full_unstemmed Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period
title_short Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period
title_sort brain white-matter changes associated with symptomatic acute covid-19 infection in the neonatal period
topic Case Illustrated
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165867/
https://www.ncbi.nlm.nih.gov/pubmed/37193002
http://dx.doi.org/10.1016/j.idcr.2023.e01796
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