Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells

E3 ubiquitin ligases are important components of the ubiquitin protease system. This family includes many proteins, which can catalyze the ubiquitination of a variety of protein substrates and promote the degradation of them by the proteasome system. Recent studies have shown that E3 ubiquitin ligas...

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Autores principales: Feng, Jun, Yin, Huimei, Baturuhu, Dai, Yonghui, Dai, Fuxiao, Xu, Junjun, Chen, Zhili, Liu, Yanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165996/
https://www.ncbi.nlm.nih.gov/pubmed/37168980
http://dx.doi.org/10.3389/fendo.2023.1124041
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author Feng, Jun
Yin, Huimei
Baturuhu,
Dai, Yonghui
Dai, Fuxiao
Xu, Junjun
Chen, Zhili
Liu, Yanyan
author_facet Feng, Jun
Yin, Huimei
Baturuhu,
Dai, Yonghui
Dai, Fuxiao
Xu, Junjun
Chen, Zhili
Liu, Yanyan
author_sort Feng, Jun
collection PubMed
description E3 ubiquitin ligases are important components of the ubiquitin protease system. This family includes many proteins, which can catalyze the ubiquitination of a variety of protein substrates and promote the degradation of them by the proteasome system. Recent studies have shown that E3 ubiquitin ligase plays a key role in the process of fetal development and placental formation. It affects the biological behavior of placental trophoblast cells, leading to a series of pregnancy complications that threaten mothers and babies greatly. This review focuses on the regulation, target and mechanism of E3 ubiquitin ligase on the biological behavior of human placental trophoblast cells.
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spelling pubmed-101659962023-05-09 Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells Feng, Jun Yin, Huimei Baturuhu, Dai, Yonghui Dai, Fuxiao Xu, Junjun Chen, Zhili Liu, Yanyan Front Endocrinol (Lausanne) Endocrinology E3 ubiquitin ligases are important components of the ubiquitin protease system. This family includes many proteins, which can catalyze the ubiquitination of a variety of protein substrates and promote the degradation of them by the proteasome system. Recent studies have shown that E3 ubiquitin ligase plays a key role in the process of fetal development and placental formation. It affects the biological behavior of placental trophoblast cells, leading to a series of pregnancy complications that threaten mothers and babies greatly. This review focuses on the regulation, target and mechanism of E3 ubiquitin ligase on the biological behavior of human placental trophoblast cells. Frontiers Media S.A. 2023-04-14 /pmc/articles/PMC10165996/ /pubmed/37168980 http://dx.doi.org/10.3389/fendo.2023.1124041 Text en Copyright © 2023 Feng, Yin, Baturuhu, Dai, Dai, Xu, Chen and Liu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Feng, Jun
Yin, Huimei
Baturuhu,
Dai, Yonghui
Dai, Fuxiao
Xu, Junjun
Chen, Zhili
Liu, Yanyan
Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells
title Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells
title_full Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells
title_fullStr Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells
title_full_unstemmed Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells
title_short Research progress of E3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells
title_sort research progress of e3 ubiquitin ligase regulating biological behavior of human placental trophoblast cells
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10165996/
https://www.ncbi.nlm.nih.gov/pubmed/37168980
http://dx.doi.org/10.3389/fendo.2023.1124041
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