Syngap1 Disruption Induced by Recombination between Inverted loxP Sites Is Associated with Hippocampal Interneuron Dysfunction

SYNGAP1 haploinsufficiency in humans causes intellectual disability (ID). SYNGAP1 is highly expressed in cortical excitatory neurons and, reducing its expression in mice accelerates the maturation of excitatory synapses during sensitive developmental periods, restricts the critical period window for...

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Detalles Bibliográficos
Autores principales: Khlaifia, Abdessattar, Jadhav, Vidya, Danik, Marc, Badra, Théo, Berryer, Martin H., Dionne-Laporte, Alexandre, Chattopadhyaya, Bidisha, Di Cristo, Graziella, Lacaille, Jean-Claude, Michaud, Jacques L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166128/
https://www.ncbi.nlm.nih.gov/pubmed/37072176
http://dx.doi.org/10.1523/ENEURO.0475-22.2023

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