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Niraparib with Abiraterone Acetate and Prednisone for Metastatic Castration-Resistant Prostate Cancer: Phase II QUEST Study Results

Niraparib (NIRA) is a highly selective inhibitor of poly (adenosine diphosphate-ribose) polymerase, PARP1 and PARP2, which play a role in DNA repair. The phase II QUEST study evaluated NIRA combinations in patients with metastatic castration-resistant prostate cancer who were positive for homologous...

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Detalles Bibliográficos
Autores principales:	Chi, Kim N, Fleshner, Neil, Chiuri, Vincenzo Emanuele, Van Bruwaene, Siska, Hafron, Jason, McNeel, Douglas G, De Porre, Peter, Maul, Raymond Scott, Daksh, Mahesh, Zhong, Xiaogang, Mason, Gary E, Tutrone, Ronald F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166146/ https://www.ncbi.nlm.nih.gov/pubmed/36994854 http://dx.doi.org/10.1093/oncolo/oyad008

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