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Rheumatoid Vasculitis Presenting with Incidental Renal Infarcts: Case Report and Literature Review

Rheumatoid vasculitis is a rare and late complication of rheumatoid arthritis, affecting small to medium sized vessels. Inflammation in the vessel wall produces an occlusive vasculopathy with downstream infarction. We present the case of a 70-year-old female with long standing stable RA status post...

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Autores principales: Halilu, Fatima, Hauptman, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Greater Baltimore Medical Center 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166213/
https://www.ncbi.nlm.nih.gov/pubmed/37168062
http://dx.doi.org/10.55729/2000-9666.1156
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author Halilu, Fatima
Hauptman, Howard
author_facet Halilu, Fatima
Hauptman, Howard
author_sort Halilu, Fatima
collection PubMed
description Rheumatoid vasculitis is a rare and late complication of rheumatoid arthritis, affecting small to medium sized vessels. Inflammation in the vessel wall produces an occlusive vasculopathy with downstream infarction. We present the case of a 70-year-old female with long standing stable RA status post recent COVID-19 vaccination admitted with community acquired Legionnaires disease found to have an incidental renal infarct on chest imaging without a clear etiology. She improved from a respiratory standpoint but then had a fever spike with repeat imaging showing a second renal infarct and CT angiography showing extensive beading with aneurysmal dilation in the bilateral hepatic and renal arteries consistent with vasculitis. Given extensive RA history, there was a high index of suspicion for rheumatoid vasculitis and she was treated with pulse steroids followed by Rituximab with tapering of steroids and clinical recovery. Her presentation is unique given the salient features, extensive multi-vessel disease without localizing symptoms and potential role of Legionella infection or COVID-19 vaccine in immune activation.
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spelling pubmed-101662132023-05-09 Rheumatoid Vasculitis Presenting with Incidental Renal Infarcts: Case Report and Literature Review Halilu, Fatima Hauptman, Howard J Community Hosp Intern Med Perspect Case Report Rheumatoid vasculitis is a rare and late complication of rheumatoid arthritis, affecting small to medium sized vessels. Inflammation in the vessel wall produces an occlusive vasculopathy with downstream infarction. We present the case of a 70-year-old female with long standing stable RA status post recent COVID-19 vaccination admitted with community acquired Legionnaires disease found to have an incidental renal infarct on chest imaging without a clear etiology. She improved from a respiratory standpoint but then had a fever spike with repeat imaging showing a second renal infarct and CT angiography showing extensive beading with aneurysmal dilation in the bilateral hepatic and renal arteries consistent with vasculitis. Given extensive RA history, there was a high index of suspicion for rheumatoid vasculitis and she was treated with pulse steroids followed by Rituximab with tapering of steroids and clinical recovery. Her presentation is unique given the salient features, extensive multi-vessel disease without localizing symptoms and potential role of Legionella infection or COVID-19 vaccine in immune activation. Greater Baltimore Medical Center 2023-03-10 /pmc/articles/PMC10166213/ /pubmed/37168062 http://dx.doi.org/10.55729/2000-9666.1156 Text en © 2023 Greater Baltimore Medical Center https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ).
spellingShingle Case Report
Halilu, Fatima
Hauptman, Howard
Rheumatoid Vasculitis Presenting with Incidental Renal Infarcts: Case Report and Literature Review
title Rheumatoid Vasculitis Presenting with Incidental Renal Infarcts: Case Report and Literature Review
title_full Rheumatoid Vasculitis Presenting with Incidental Renal Infarcts: Case Report and Literature Review
title_fullStr Rheumatoid Vasculitis Presenting with Incidental Renal Infarcts: Case Report and Literature Review
title_full_unstemmed Rheumatoid Vasculitis Presenting with Incidental Renal Infarcts: Case Report and Literature Review
title_short Rheumatoid Vasculitis Presenting with Incidental Renal Infarcts: Case Report and Literature Review
title_sort rheumatoid vasculitis presenting with incidental renal infarcts: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166213/
https://www.ncbi.nlm.nih.gov/pubmed/37168062
http://dx.doi.org/10.55729/2000-9666.1156
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