Enhanced sodium channel inactivation by temperature and FHF2 deficiency blocks heat nociception

Transient voltage-gated sodium currents are essential for the initiation and conduction of action potentials in neurons and cardiomyocytes. The amplitude and duration of sodium currents are tuned by intracellular fibroblast growth factor homologous factors (FHFs/iFGFs) that associate with the cytopl...

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Detalles Bibliográficos
Autores principales: Marra, Christopher, Hartke, Timothy V., Ringkamp, Matthias, Goldfarb, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166761/
https://www.ncbi.nlm.nih.gov/pubmed/36607284
http://dx.doi.org/10.1097/j.pain.0000000000002822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166761/
https://www.ncbi.nlm.nih.gov/pubmed/36607284
http://dx.doi.org/10.1097/j.pain.0000000000002822

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