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TPX2 promotes ovarian tumorigenesis by interacting with Lamin A/C and affecting its stability

OBJECTIVE: Ovarian cancer (OC) is one of the fatal gynecologic malignancies. However, there are no effective prognostic or therapeutic indicators for OC. Herein, we aim to reveal the potential function of targeting protein for Xklp2 (TPX2) in OC progression. METHODS: Immunohistochemical and bioinfor...

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Detalles Bibliográficos
Autores principales: Meng, Xin, Cao, Jiazhen, Zheng, Hui, Ma, Xiaolu, Wang, Yanchun, Tong, Ying, Xie, Suhong, Lu, Renquan, Guo, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166900/
https://www.ncbi.nlm.nih.gov/pubmed/36789877
http://dx.doi.org/10.1002/cam4.5683