Differences in clinical characteristics and prognosis between breast neuroendocrine carcinoma and breast invasive ductal carcinoma: A multicentre population‐based study from China

AIM: We constructed a multicentre cohort in China to analyse the differences in clinical characteristics, treatment strategies and prognoses between breast neuroendocrine carcinoma (NEC) and invasive ductal carcinoma (IDC) of the breast. METHODS: All patients with early‐stage breast cancer who atten...

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Detalles Bibliográficos
Autores principales: Wang, Ding‐yuan, Li, Shuo‐feng, Gao, Song‐lin, Yuan, Peng, Zhang, Bai‐lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
BRIEF COMMUNICATION
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166936/
https://www.ncbi.nlm.nih.gov/pubmed/36952359
http://dx.doi.org/10.1002/cam4.5819
Descripción
Sumario:AIM: We constructed a multicentre cohort in China to analyse the differences in clinical characteristics, treatment strategies and prognoses between breast neuroendocrine carcinoma (NEC) and invasive ductal carcinoma (IDC) of the breast. METHODS: All patients with early‐stage breast cancer who attended three hospitals in Beijing from 2000 to 2018 were included in the study. We used propensity score matching to make a 1:3 match between NEC and IDC. RESULTS: After propensity score matching, 153 patients with IDC and 51 patients with NEC were analysed. Multivariate Cox regression showed that compared to patients with IDC, patients with NEC had a worse disease‐free survival (HR = 2.94, 95% CI: 1.69–5.12, p < 0.001). CONCLUSION: NEC patients have a worse disease‐free survival than IDC patients.

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